IS THERE ANY SIGNIFICANT CORRELATION BETWEEN AGE, SEX, BMI, CLINICAL AND ENDOSCOPIC FINDINGS IN DYSPEPSIA?

Abstract

Introduction: Dyspepsia is a common complaint in clinical practice and is present in various clinical dilemmas. Though dyspeptic patient show wide spectrum of symptoms, some are found to have structural cause and others have functional cause. Aim: The aim of the study was to correlate clinical and endoscopic findings in patient with dyspepsia: and also assess correlation of H. Pylori infection with endoscopic findings. Method: The prospective observational study was conducted at tertiary care centre from July 2015 to September 2017 on total 114 cases presented with dyspepsia after considering specific inclusion and exclusion criteria. A detailed history was taken and clinical examination was carried out. All patients underwent oesophagogastroduodeno (OGD) scopy. Two endoscopic mucosal biopsies were taken from the antrum and body of the stomach for rapid urease test (RUT). Results: No correlation was observed between prevalence of dyspepsia and age, sex or body mass index (BMI). In majority of patients clinically suspected findings were confirmed on endoscopy. Majority of patients were found to have structural findings on endoscopy. In most of the subjects with positive endoscopy findings in stomach and/or duodenum had H. pylori infection. Demographic factors like smoking, alcohol, excessive consumption of coffee or tea, NSAIDs or aspirin use were found to have influencing effects on prevalence of dyspepsia. Conclusion: Structural dyspepsia is more common in our study than functional dyspepsia. Significant correlation was observed between clinical and endoscopic findings in patient with dyspepsia. Keywords: Dyspepsia; Oesophagogastroduodenoscopy; H. pylori; Gastroesophageal reflux disease.