Abstract
<strong>PICO question</strong><br /><p>In dogs and cats, is the oral administration of garlic, compared to no treatment, efficacious at preventing or reducing the intestinal worm burden (species found in the UK)?</p><strong>Clinical bottom line</strong><br /><p>No studies were identified that investigated the efficacy of garlic at preventing intestinal worm burden. Garlic reduced egg and/or larvae counts in the worm species studied. However, where measured, egg and larvae count rapidly (2 days) returned to pretreatment levels once dietary garlic was discontinued. None of the studies included adulticidal action as an outcome measure. In the absence of research to demonstrate high levels of adulticidal action against a range of intestinal wormers at therapeutic, non-toxic levels in cats and dogs, clients should be advised that garlic has not been demonstrated to be an effective anthelmintic (either for multiple or single species use) for use in dogs and cats either to prevent or to treat an intestinal worm burden.</p><br /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/oa-icon.jpg" alt="Open Access" /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/pr-icon.jpg" alt="Peer Reviewed" />
Highlights
Different breeds, and an age range of 2 months–4 years were used, but it is not possible to distinguish how this was distributed across the two groups
This study found that larvae count of Ancylostoma caninum decreased during daily dosing with garlic, but eggs per gram of faeces remained similar following a five-day dosing period
CONFLICT OF INTEREST The author declares no conflicts of interest
Summary
Population: Two different populations of dogs were used. Group one: unwormed dogs at a Romanian rescue centre. The dose administered of both the tincture and the pumpkin oil was weight dependent, and was given per os twice daily for 5 days. Day 1–13: at some point over these 13 days each dog was given a weight dependent twice daily dose of the tincture plus the pumpkin oil for 5 days. The actual days this was administered on are not reported. EPG = Eggs per gram Main findings: In summary, for both groups of dogs, the egg count of the three (relevant to PICO question): species present was considerably lower following the intervention. Trichocephalus spp.: - Day 0: 508.30 ± 83.08 - Day 14: 50.00 ± 18.26 - Effectiveness: 93.82%
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