Abstract

Diabetic foot is associated with a low quality of life since physical disabilities, mood disturbances and psychological disorders are frequent. One of the most important biological processes to ensure quality of life is sleep. Sleep disorders can impair glycemic control in patients with diabetes mellitus or even cause long-term type 2 diabetes mellitus. The aim of this study is to carry out a scoping review about the association between sleep cycle disorders and diabetic foot. PubMed, Scopus, CINAHL, PEDro, Cochrane Library, SCIELO and EMBASE databases were chosen for the search and the following terms were used: “diabetic foot”,“sleep*”,“rest-activity”,“mood” and“behavior”. All the studies should include outcome variables about sleep and diabetic foot. Finally, 12 articles were selected, all of whichwere observational. The most frequent variables were those regarding diabetic foot ulcer aspects and diabetic neuropathy on one side, and obstructive sleep apnea, sleep duration and sleep quality on the other side. The results suggest that there is a possible association between obstructive sleep apnea and the presence or history of diabetic foot ulcers. No direct associations between sleep quality or sleep duration and diabetic foot or diabetic foot ulcer variables have been found.

Highlights

  • In many cases, diabetes mellitus (DM) leads to several complications, of which diabetic foot (DF) is one of the most frequent [1]

  • Diabetes mellitus (DM) leads to several complications, of which diabetic foot (DF) is one of the most frequent [1]. It likely begins with the onset of diabetic neuropathy (DN) and peripheral arterial disease (PAD) [2].Unless this situation is prevented, it can result in diabetic foot ulcers (DFUs), which tend to become infected and show poor healing [3,4]

  • The main reason for exclusion was the absence of variables related to the sleep cycle or DF in the main objective of the study

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Summary

Introduction

Diabetes mellitus (DM) leads to several complications, of which diabetic foot (DF) is one of the most frequent [1]. It likely begins with the onset of diabetic neuropathy (DN) and peripheral arterial disease (PAD) [2].Unless this situation is prevented, it can result in diabetic foot ulcers (DFUs), which tend to become infected and show poor healing [3,4]. Along with the mortality and morbidity of DFUs, the economic consequences are high. In Europe, the cost of treating DFUs varies from approximately 4500 to 16,800EUR per patient [7]

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