Abstract
Extended blastocyst culture and embryo transfer (ET) has proven to result in higher pregnancy (PR) and live birth (LBR) rate compared to cleavage stage transfer. While this is thought to be due to greater oocyte yield, optimal embryo selection and improved embryo-endometrium synchrony, limited data exists on the benefits of blastocyst culture in advanced maternal age (AMA) (>40 years) women whose embryos may be less likely to resist prolonged in vitro conditions. We compared pregnancy outcomes of those undergoing d-3 vs d-5 ET in AMA women and secondarily analyzed those who had a d-3 ET, but otherwise met criteria for extended culture (3 or more good morphology embryos on day 3) to those undergoing d-5 ET.
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