Is there a relationship between epicardial adipose tissue, inflammatory markers and prognosis in COVID-19 in patientsunder 65years?

Abstract

Aim: This studyinvestigated the prognostic value of epicardial adipose tissue volume (EATV)attenuation (EATA) in patients admitted to the intensive care unit forCOVID-19. Materials & methods: C-reactive protein (CRP), fasting blood glucose (FBG), neutrophil and lymphocyte counts, neutrophil-to-lymphocyte ratio (NLR) and lymphocyte-to-CRP ratio (LCR) were recorded. Receiver operator characteristicanalysis was performed for EATV and EATA. Results: The study included 190 patients (65 deceased, 125 discharged, mean age 52.01±9.6years). The deceased group had significantly higher FBG and CRP values and significantly lower platelet count and LCR values. EATA (cut-off: -92.38 HU) and EATV (cut-off: 15.74 cm2) were significantly higher in the deceased group. EATV had a correlation with age, FBG, CRP, neutrophil, NLRand LCR, whereas EATA correlated with involvement on CT scan. Conclusion: EATV is associated with inflammatory parameters, whereas EATA is associated with CT scan involvement and can be used to predict mortality in young adult patients.