Is there a relationship between chondroid neoplasia and AB0 blood groups?

Abstract

Aim : AB0 and Rh blood groups have been associated with various malignancies. This study aims to investigate the relationship between AB0/Rh blood groups and chondroid neoplasia.
 Material and Methods : We evaluated 276 patients with chondroid neoplasia retrospectively. The blood groups and tumor localization of the patients who were operated between 2014-2019 were recorded. 129 patients who donated blood to our hospital in 2019 constituted the control group.We compared the demographic characteristics and blood groups of the patients with the control group using the chi-square test. 
 Results : The mean age was 52±14.6, 49±15.9, and 37±10.3 years, respectively, for enchondroma, chondrosarcoma and the control group. The tumor was mostly localized to the distal femur in both enchondroma and chondrosarcoma patients. Although the 0Rh (+) blood group rate was higher and the B (Rh (+) blood group rate was lower in patients with enchondroma and chondrosarcoma compared to the control group, this difference was not statistically significant. The A and AB blood group rates of the case and control groups were similar.
 Conclusion : There was no relationship between AB0 blood groups and chondroid neoplasia. Studies investigating the relationship of different benign and malignant bone tumors with AB0 and Rh blood groups in large patient series are needed.