Is there a place for indwelling transurethral catheterization in women with febrile urinary tract infection? A prospective randomized trial.

Abstract

To assess the common practice to transiently place an indwelling transurethral catheter in case of hospitalization of women with febrile urinary tract infections. So far, this intervention has not been scientifically investigated. Inclusion criteria were female gender, a leucocyte esterase-positive urine dipstick analysis (≥ 250) from urine obtained with a catheter and fever > 38°C. Patients were randomized 1:1 to either receive an indwelling catheter French 16 or not. The catheter was removed after 24h without fever (< 37.5°C). Principal exclusion criteria were a post void residual volume exceeding 50mL or abnormalities of the urinary tract. Hospital stay and fever in days, the amount of analgetic medication needed and the laboratory parameters WBC and CRP-measured on the day of admission and in predefined intervals thereafter-were study endpoints. 75 patients were included in the final analysis, 36 in the catheter group and 39 in the no-catheter group. Mean age was 39.4 ± 17.7years and 39.8 ± 15.5years, respectively (p > 0.05). The mean length of catheterisation was 3.6 ± 1.6days in the catheter group. There were no differences between the two groups regarding duration of hospitalization and fever, or the amount of analgetic medication needed (all p > 0.05). Additionally, there was no difference in time to WBC < 10G/L or CRP < 100mg/L (all p > 0.05). This prospective, randomized trial provides no evidence to support routine insertion of an indwelling catheter in women with febrile urinary tract infection requiring hospital admission.