Abstract
AIM: to evaluate the significance of high-resolution anoscopy (HRA) in diagnostics of inflammatory and thrombotic changes in hemorrhoid piles and to assess the efficacy of micronized purified favonoid fraction (MPFF) in patients with inflammatory thrombotic changes of hemorrhoids according to HRA results in the preoperative conservative treatment of hemorrhoids. PATIENTS AND METHODS: a prospective cohort study included 77 patients with grade III chronic hemorrhoids. Patients were divided into 3 groups depending on the degree of development of inflammatory and thrombotic changes according to the HRA. The 3 group included patients with preoperative conservative treatment by MPFF. All patients underwent Milligan-Morgan procedure with further histological study of removed piles. RESULTS: it was found that the diagnostic sensitivity of the HRA in detection of inflammatory thrombotic changes was 91.3 % (CI=83.6-96.2 %), and diagnostic specificity - 40 % (CI=19-64 %). HRA diagnostic accuracy was 82.1 % (p=0.001). A 30 % decrease in the number of removed piles with moderate inflammatory thrombotic changes after MOFF therapy has also been revealed. CONCLUSION: HRA permits to determine the severity of thrombotic inflammatory changes, which is extremely importantfor the management of patients with acute hemorrhoids.
Highlights
AIM: to evaluate the significance of high-resolution anoscopy (HRA) in diagnostics of inflammatory and thrombotic changes in hemorrhoid piles and to assess the efficacy of micronized purified flavonoid fraction (MPFF) in patients with inflammatory thrombotic changes of hemorrhoids according to HRA results in the preoperative conservative treatment of hemorrhoids
Patients were divided into 3 groups depending on the degree of development of inflammatory and thrombotic changes according to the HRA
RESULTS: it was found that the diagnostic sensitivity of the HRA in detection of inflammatory thrombotic changes was 91.3 % (CI=83.6-96.2 %), and diagnostic specificity – 40 % (CI=19-64 %)
Summary
Khitaryan A.G.1,2, Alibekov A.Z.1,2, Kovalev S.A.1,2, Shatov I.A.1, Aluhanyan O.A.3, Voronova O.V.1,2, Burdakov I.Y.1 1 Rostov State Medical University, Rostov-on-Don, Russia 2 Road clinical hospital on st. Rostov-Main OAO «RJD», Rostov-on-Don, Russia 3 Kuban State Medical University, Krasnodar, Russia. Patients were divided into 3 groups depending on the degree of development of inflammatory and thrombotic changes according to the HRA. RESULTS: it was found that the diagnostic sensitivity of the HRA in detection of inflammatory thrombotic changes was 91.3 % (CI=83.6-96.2 %), and diagnostic specificity – 40 % (CI=19-64 %). A 30 % decrease in the number of removed piles with moderate inflammatory thrombotic changes after MOFF therapy has been revealed. CONCLUSION: HRA permits to determine the severity of thrombotic inflammatory changes, which is extremely important for the management of patients with acute hemorrhoids. Впервые ВРА в прослизистой анального канала является высокораз- ктологии была применена с целью диагностики. Оценить эффективность применения флеботонических препаратов у пациентов с воспалительно-тромботическими изменениями геморроидальных узлов по данным ВРА. Оценить эффективность применения флеботонических препаратов у пациентов с воспалительно-тромботическими изменениями геморроидальных узлов по данным ВРА. в предоперационном периоде
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