Abstract
To assess the benefit of the periprostatic administration of lidocaine previously to ultrasound-guided prostate biopsy. In the period from April to October 2002, forty patients underwent ultrasound-guided prostate biopsy due to increased PSA or abnormal digital rectal examination. A randomized double-blind study was performed, where the patients received an injection of lidocaine 2% or saline solution, in a total of 10 ml periprostatic. Immediately following the biopsy, the pain associated to the procedure was assessed, using a visual analogical scale from 0 to 10. The mean number of fragments collected per patient in the biopsies was 11.3. The statistical analysis used for assessment of pain was the Student's t, with p < 0.05 being significant. The groups were homogeneous concerning the anthropometrical data. In relation to pain, those patients in the groups that underwent biopsy with the use of lidocaine presented a maximum score of 6, while in the group that underwent biopsy with the use of saline solution, 4 patients presented score 7 ou 8. The mean score and standard deviation with lidocaine were 2.55 +/- 2.34 (CI 95% = 1.53 to 3.57) and with saline solution were 3.75 +/- 2.52 (CI 95% = 2.66 +/- 4.84) with no statistical significant difference between the groups. The lidocaine injection did not show statistical difference when compared with saline solution in the periprostatic blockade during echo-guided prostate biopsy.
Highlights
The transrectal ultrasound-guided biopsy of the prostate is an integrant part of the assessment and diagnosis of prostate cancer in patients with high prostate-specific antigen (PSA) or abnormalities on the digital rectal examination [1].The majority of urologists have performed this procedure without anesthesia or sedation [2]
The lidocaine injection did not show statistical difference when compared with saline solution in the periprostatic blockade during echo-guided prostate biopsy
Patients were randomly distributed into 2 groups with 20 patients each, receiving periprostatic injection of 2% lidocaine without vasoconstrictor or 0,9% saline solution, in unlabeled 10-ml syringes that had been prepared by a nurse
Summary
In the period from April to October 2002, forty patients underwent ultrasound-guided prostate biopsy due to increased PSA or abnormal digital rectal examination. A randomized double-blind study was performed, where the patients received an injection of lidocaine 2% or saline solution, in a total of 10 ml periprostatic. Following the biopsy, the pain associated to the procedure was assessed, using a visual analogical scale from 0 to 10. The mean number of fragments collected per patient in the biopsies was 11.3. The statistical analysis used for assessment of pain was the Student’s t, with p < 0.05 being significant
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
