Is the corpus uteri a suitable site for embryo transfer in the pig?

Abstract

Numerous attempts to establish a practicable means of non-surgical embryo transfer in pigs were unsuccessful until instruments were developed to permit deposition of embryos deep inside a uterine horn. Recently, however, successful non-surgical transfer of embryos to the uterine body in non-sedated recipients has been reported. These reports have prompted us to present data from a study that addresses the question of whether the commonly experienced low pregnancy rates following transfers to the corpus uteri results from the inability of endometrial receptors to recognize the presence of embryos or to the prevailing unfavorable local conditions. Blastocysts were transferred to the corpus uteri of recipients in which maintenance of pregnancy was assured by the transfer of additional embryos to the tip of a uterine horn. Embryos from pigmented and unpigmented donors were used to be able to differentiate between fetuses from embryos transferred to different sites. Fewer fetuses developed from embryos transferred to the corpus uteri than from embryos transferred to the uterine horn. This leads to the conclusion that prolonged retention of blastcysts in the uterine body under conditions inappropriate for their stage of development is responsible for an unsatisfactory pregnancy rate.