Abstract
PurposeTo assess the relationship between the axial length and post-LASIK regression in myopic patients.MethodsThis is a retrospective case series study conducted at a private eye centre, Ismailia, Egypt. The clinical records of the patients, who experienced LASIK to correct myopia from January 2016 to January 2018, were analysed for myopic regression. The patients were operated on, examined, and followed-up 1 year by one surgeon (AAG).ResultsThis study included 1219 patients (2316 eyes) with myopia. Mean ± SD of pre-operative spherical equivalent (SE) was − 4.3 ± 2.1D, range (− 0.50 to − 10.0D). Mean ± SD age of the patients was 26.4 ± 6.8 years, range (21 to 50 years). Male to female ratio was 30.5 to 69.5%. The cumulative incidence rate of myopic regression according to the medical records of the patients was 25.12% (582 eyes out of total 2316 eyes) along the 2 years of this study (12.6% per year). Of the total patients, 14.94% had pre-operative high myopia, 35.84% had pre-operative moderate myopia, and 49.2% had pre-operative low myopia. Of the patients with myopic regression, 52.6% had pre-operative high myopia, 34% had pre-operative moderate myopia, and 13.4% had pre-operative low myopia. The mean ± SD of the axial length of the patients with myopic regression was 26.6 ± 0.44 mm, range (26.0 to 27.86 mm), while the mean ± SD of the axial length of other patients with stable refraction was 24.38 ± 0.73 mm, range (22.9 to 25.9 mm) (t test statistic = 69.3; P value < 0.001).ConclusionsPre-operative high axial length increases the risk of myopic regression after LASIK.
Highlights
Post-laser in situ keratomileusis myopic regression can be defined as gradual, incomplete, or complete loss of primary correction that limits the efficiency, predictability, and longterm stability of laser in situ keratomileusis (LASIK) [1]. LASIK techniques and surgeon experience have improved over the past 20 years resulting in better outcomes, Graefes Arch Clin Exp Ophthalmol (2021) 259:777–786 myopic regression after LASIK is inevitable, and the exact mechanism of it is unclear and under-explored [2]
Hersh et al [7] recorded a 10.5% incidence of myopic regression in their study (3-year follow-up period). They stated that high primary corrections, astigmatism, and old age were significant risk factors for it
The cumulative incidence rate of myopic regression according to the medical records of the patients was 25.12% (582 eyes out of total 2316 eyes) along the 2 years of this study (12.6% per year)
Summary
Post-laser in situ keratomileusis myopic regression can be defined as gradual, incomplete, or complete loss of primary correction that limits the efficiency, predictability, and longterm stability of laser in situ keratomileusis (LASIK) [1]. LASIK techniques and surgeon experience have improved over the past 20 years resulting in better outcomes, Graefes Arch Clin Exp Ophthalmol (2021) 259:777–786 myopic regression after LASIK is inevitable, and the exact mechanism of it is unclear and under-explored [2]. Patel et al [6] recorded a myopic regression rate of 16% along the 3-month follow-up period of their study. Hersh et al [7] recorded a 10.5% incidence of myopic regression in their study (3-year follow-up period). They stated that high primary corrections, astigmatism, and old age were significant risk factors for it. Liu et al [8] recorded a rate of 21% myopic regression along 5 years of their study. Randleman et al [9] recorded a 6.3% enhancement rate along 1-year follow-up period and stated that patients with high myopic errors were more expected to have enhancement. In long-term studies, Alio et al [10] recorded retreatment rates ranging from 20 to 27% in their study with 10 years follow-up
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Graefe's Archive for Clinical and Experimental Ophthalmology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
