Abstract
Quifenadine , a drug developed in the laboratory of M.D.Mashkovsky in the 1970s, is one of the first examples of the creation of a new class of nonsedative antihistamines of multifunctional action, combining high selective activity to block type 1 histamine receptors, the ability to block the action of serotonin and enhance histaminase activity in tissues. The article describes the latest data on the study of the pharmacokinetics of the drug, presents studies on the efficacy and safety of quifenadine. Currently, the question remains open to which generation of antihistamines to include quinuclidine, considering all the described characteristics.
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