Abstract
Is primary thoracic ewing sarcoma aggressive than others? seventeenyears' experience
Highlights
Ewing sarcoma is an aggressive malignancy with a high incidence of local recurrence and distant metastasis, which are important prognostic factors
A 19-year-old male who was operated on due to post-traumatic pleural hematoma and Ewing sarcoma (ES) was detected during surgery, and a 4-year-old female patient was evaluated using Positron emission tomography (PET)/computed tomography (CT) in the postoperative period for staging; both these patients showed no evidence of distant metastasis
We report the clinical features, treatment strategies and outcomes, complications, and survival of 14 patients with thoracic ES who underwent surgical resection
Summary
Ewing sarcoma is an aggressive malignancy with a high incidence of local recurrence and distant metastasis, which are important prognostic factors. Chemotherapy, and local radiation therapy, when indicated, constitutes the optimal treatment. Thoracic sarcomas frequently involve the ribs, characterized by indolent progression. Hereby, these tumors are often diagnosed at a locally advanced stage, with massive pleural cavity involvement, or even at a metastatic stage (in 25% of cases) [1]. Ewing sarcoma (ES) is an uncommon aggressive malignant tumor of the bone and/or soft tissue and belongs to peripheral primitive neuroectodermal tumor (PNET) family of tumors. The treatment modalities and tumor-related factors of chest wall ES and lung parenchyma were evaluated. Conclusions: Complete tumor resection is the most effective treatment for thoracic ES and multimodal therapy (surgical resection, chemotherapy, and local radiation therapy), which is recommended when indicated, constitutes the optimal treatment for ES. The follow-up periods must be short and should be maintained long term for late relapses
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