Abstract
Tuesday 09 August – Scientific Session 5/1140–1200 WallShearStress in theDeterminationofConduitPatency for Coronary Artery Graft Surgery Michael Byrom1,2,3,∗, Michael Vallely 1,2,3, Paul Bannon1,2,3 1 Royal Prince Alfred Hospital, Sydney, Australia 2 The Baird Institute, Sydney, Australia 3 University of Sydney, Sydney, Australia Introduction: Conduits known to exhibit enhanced patency include those to larger target vessels, with tighter proximal stenoses and greater runoff, and sequential grafts tomultiplearteries.Other factorshave recentlybeen questioned including whether arterial grafts are superior to vein or even whether vein can match the patency of the internal mammary artery. These and other determinants can be explained by understanding the role of wall shear stress in the determination of conduit patency, potentially enabling the maximisation of patency outcomes by guiding conduit selection and technique. Methods: An extensive research library in conduit design and performance covering over 1200 journal articles and textbookswas supplemented by focusedMedline searches for relevant articles. Results: Thrombogenicity and intimal hyperplasia represent themost common intrinsic causes of coronary graft Reference [1] Hadinata IE, Hayward PAR, Hare DL, Matalanis GS, Seevanayagam S, Rosalion A, et al. Choice of conduit for the right coronary system: 8-year analysis of radial artery patency and clinical outcomes trial. Ann Thorac Surg 2009;88:1404–9. [2] Souza DSR, Johansson B, Bojo L, Karlsson R, Geijer H, Fibey D, et al. Harvesting the saphenous vein with surrounding tissue for CABG provides long-term graft patency comparable to the left internal thoracic artery: results of a randomized longitudinal trial. JCTS 2006;132(2):373–8. doi:10.1016/j.hlc.2011.08.025
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