Abstract

To the Editor :—Under the title Is Penicillin a Photosensitizing Agent? Dr. Orlando Canizares (Arch. Dermat. & Syph. 52 :17 [July] 1945) reports on an interesting case. Since penicillin is such an important drug, the question whether it is also a photosensitizer deserves careful attention; therefore, I should like to comment briefly on Dr. Canizares' report. These are the facts of the case: The patient had taken sulfonamide drugs between January 6 and 19. On January 29 he had received 50,000 units of penicillin. On January 30 he took a sun bath, which was followed by a rather severe erythema. Three days later a morbilliform eruption was noticed at the areas previously most affected by the sunburn. There is no doubt that one is dealing here with some form of photodermatitis. The question is: Was it caused by the sulfonamide drugs or by the penicillin? One would first think

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