Abstract
ObjectivesTo compare the odds of depression in obese and overweight children with that in normal-weight children in the community.DesignSystematic review and random-effect meta-analysis of observational studies.Data sourcesEMBASE, PubMed and PsychINFO...
Highlights
Childhood mental illness is poorly recognised by healthcare providers and parents, despite half of all lifetime cases of diagnosable mental illness beginning by the age of 14 years. [1] Globally, depression is the leading cause of disease burden, as measured by disability adjusted life years, in children aged 10-19 years.[2]
Among overweight children drawn from specialist clinics, 23.4% are estimated to be depressed.[21] overweight children drawn from specialist clinics are not representative of children in the community and may over estimate risk.[22] the overall risk of depression in overweight children in the community remains unclear
Obesity was defined as ≥95th centile and overweight ≥ 85th centile; or using the International Obesity Task Force (IOTF) age-sex specific centiles curves correlating to 25 and 30 kg/m2 for adult overweight and obesity.[23]. We excluded studies that defined obesity using other methods such as waist circumference or body composition as these are rarely used in clinical practice
Summary
Childhood mental illness is poorly recognised by healthcare providers and parents, despite half of all lifetime cases of diagnosable mental illness beginning by the age of 14 years. [1] Globally, depression is the leading cause of disease burden, as measured by disability adjusted life years, in children aged 10-19 years.[2]. [1] Globally, depression is the leading cause of disease burden, as measured by disability adjusted life years, in children aged 10-19 years.[2] Untreated, it is associated with poor school performance and social functioning, substance misuse, recurring depression in adulthood and increased suicide risk; which is the second leading cause of preventable death among young people. Childhood obesity itself is a global public health crisis, threatening the health of future populations from physical health consequences,(14) such as cardiovascular disease, type 2 diabetes and cancer [15,16,17]. Estimates vary widely from 4% to 64%,(19, 20) due to differences in populations, study designs and measurement of weight and depression. We systematically identifying cross-sectional and prospective studies reporting concurrent or future risk of depression and performing metaanalysis to report the overall risk of depression in overweight and obese children drawn from community settings, compared with normal weight children
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