Is lactobacillus phage involved in the pathogenesis of bacterial vaginosis?

Abstract

Despite over 60 years of research, the etiology of bacterial vaginosis (BV), the most common cause of vaginal discharge, remains controversial. We investigated longitudinal changes in the vaginal microbiota prior to incident BV (iBV) using shotgun metagenomic sequencing (SMS) to elucidate the role of Lactobacillus phages.