Abstract

Background: Clinically relevant postoperative pancreatic fistula (CR-POPF) is a common complication after pancreatoduodenectomy and is associated with significant mortality. The Fistula Risk Score (FRS), incorporating pancreatic duct size, parenchymal texture, blood loss, and at-risk pathology, is a validated tool for predicting CR-POPF. Postoperative pancreatitis (POP), reflecting parenchymal injury or ischemia, has been described in up to 40% of patients after pancreatoduodenectomy, but its association with POPF remains unclear. The aim of this study was to examine the relationships between POP, FRS, and CR-POPF.

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