Abstract

Background: The Heart Failure Society of America (HFSA) and the American College of Cardiology/American Heart Association (ACC/AHA) provide guidelines for the utilization of spironolactone (S) in severe systolic heart failure (HF) and post myocardial infarction patients. Freguent monitoring of the creatinine (Cr) or creatinine clearance (CrCL) and potassium (K) levels provide insight into the renal effects of S, but little is reported regarding these levels when S is used in conjunction with other HF medications in the community setting.

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