Abstract
Background Takaytasu aortitis (TA) is an inflammatory large-vessel vasculitis of unknown origin. In rare cases, isolated aortitis (IA) is usually diagnosed by its incidental microscopic findings after ascending aortic surgery. Some of isolated aortitis are thought to be IgG-4 related disease. Methods We compared 52 TA patients and 7 IA patients who underwent aortic surgery to investigate clinical and histopathological features. Results Patients with TA were older than IA patients (M/F; 3/4) (median 56 vs 78 years; p Conclusions In comparison to IA, TA tends to show poor clinical outcome because of its multiple vascular damage. Clinically, isolated aortitis may be a distinct disease of TA. IA was also considered in case of ascending aortic aneurysm.
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