Is Increased Mean Platelet Volume a Risk Factor in Patients with Acute Deep Vein Thrombosis?

Abstract

Objective: The purpose of this retrospective study was to compare the mean platelet volume between the patients with acute deep vein thrombosis and control subjects. Patients and Methods: Data were collected retrospectively from the patients' medical records. The study group consisted of 110 patients with newly diagnosed acute deep vein thrombosis in lower extremities. An age-, gender-, and body mass index-matched control group consisted of 98 patients with normal duplex ultrasound findings. We compared the mean platelet volume in patients with acute deep vein thrombosis and control participants statistically. Results: There were no significant differences between the study and control groups in mean platelet volume (8.8 ± 1.6 vs 8.7 ± 1.3 fl, respectively; p >0.05).Age (p = 0.899), body mass index (p = 0.43), gender (p = 0.466), and platelet count (p = 0.886) were statistically similar in both groups. Conclusion: There was no significant difference in patients with acute deep vein thrombosis in mean platelet volume compared to controls statistically. According to our result, we suggest that mean platelet volume cannot be considered as an index of acute deep vein thrombosis.