Abstract

Among women who are undergoing in vitro fertilization (IVF), transfer of frozen embryo’s (FET) in the natural cycle (NC) is an effective alternative to FET in the artificial or supplemented cycle in terms of pregnancy outcomes. As NC-FET results in a lower perinatal complication rate that artificial FET, it is a preferred method to transfer frozen embryos in ovulatory women. The standard in NC-FET is modified or hospital-based NC-FET, which involves repeated ultrasounds and triggering the ovulation. From the woman’s point of view, a more natural approach to time FET using LH urine tests to allow a natural ovulation, i.e. true NC or home-based monitoring, may be desired. It is not known whether FET in the true NC results in similar ongoing pregnancy rates compared to modified NC-FET.

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