Abstract
The increased rate of fracture healing and abundant callus formation of long bone fractures in patients with concomitant severe acute traumatic head injury is a well-known orthopaedic phenomenon. Few studies, however, have reported this phenomenon being induced by acute traumatic Spinal Cord Injury (SCI). There is also a wellestablished clinical relationship between spinal cord injuries and heterotopic ossification. Research is yet to confirm accelerated bone healing in long bone fractures in patients with concomitant SCI and to establish theories about the mechanism causing it.
Highlights
The increased rate of fracture healing and abundant callus formation of long bone fractures in patients with concomitant severe acute traumatic head injury is a well-known orthopaedic phenomenon
Blood samples from different patients’ groups were processed by centrifugation and after separation of blood cells; separated sera were preserved at -850 C and used to count the number of circulating mesenchymal stem cells and monocytes in peripheral blood using the flow cytometry, in each of the above groups of patients
We tested the effect of inflicted dorsal spinal cord injury, producing paraplegia, on the bone healing of hind limb midshaft femoral osteotomy fixed by intramedullary K-wire in 12 rabbits, compared to control group of another 12 rabbits with inflicted femoral osteotomy and intra-medullary K-wire fixation only
Summary
The increased rate of fracture healing and abundant callus formation of long bone fractures in patients with concomitant severe acute traumatic head injury is a well-known orthopaedic phenomenon.
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