Is foveal thickness correlated with macular pigment optical density and with Intraocular light scatter in early age‐related maculopathy?

Abstract

Abstract Purpose The purpose of this study was to investigate the relationship of foveal thickness with macular pigment optical density (MPOD) and intraocular light scatter (IOLS) in Early Age Related Maculopathy (ARM) subjects. Methods Forty eyes of adults (age mean: 65 ± 7 years) with early Age Related Maculopathy (ARM) were investigated. All patients had undergone a complete ophthalmic examination to select the subjects. Foveal thickness parameters were obtained using optical coherence tomography (OCT: Topcon 3D OCT‐1000). Macular pigment optical density at the fovea was measured with the Metropsis Test (Cambridge Research Systems. Ltd. UK) and intraocular light scatter was measured using the C‐Quant straylight meter (Oculus AG, Germany). Results Mean foveal thickness was 226.44 ± 22.56 microns, mean MPOD was 0.22 ± 0.29 log units and mean IOLS was 1.14 ± 0.18 log units. With the regression analysis of linear model, we did not find a significant correlation between foveal thickness and MPOD and neither between foveal thickness and IOLS in early ARM subjects. Conclusion No correlation was found between foveal thickness and macular pigment optical density and between foveal thickness and intraocular light scatter in early ARM subjects.