Abstract
Background: The finding of mediastinal lymphadenopathy (ML) frequently involves a work-up for malignancy. This includes positron emission tomography (PET) prior to tissue diagnosis, which is often obtained by endoscopic ultrasound via fine-needle aspiration (EUS-FNA). A recent study has demonstrated that EUS-FNA for diagnosing malignant ML has a PPV of 100% and a NPV of 97% (Eloubeidi et al.). We investigated whether prior diagnosis of malignancy influenced findings on EUS-FNA of PET-positive ML and whether EUS-FNA added accuracy to PET.
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