Is early repeat surgery a feasible concept for potential incomplete resection in acromegaly?

Abstract

Transsphenoidal surgery is the treatment of choice for acromegaly. Cure is defined by normalization of age-related IGF-1 and sufficient suppression of GH in the oral glucose tolerance test (OGTT). We investigated, if early postoperative hormone testing gives reliable information whether complete resection of a tumor was achieved and compared these findings with further follow-up data.