Is dyslipidemia associated to mortality in patients with COVID-19?

Abstract

BackgroundThe COVID-19 pandemic has affected millions of people worldwide, so it is necessary to determine risk factors associated with severe disease and mortality, to make a risk stratification for the appropriate use of hospital resources. Except for a few cases, most deaths from this disease are related to the patient's comorbidities. Several observational studies have reported an association between dyslipidemia and the risk of severe COVID-19 disease, but there is no consensus. Objective: The present study aimed to determine whether there is an association between dyslipidemia and mortality in patients with COVID-19. MethodsLipid profiles were performed in 200 Guatemalan patients with COVID-19 admitted to the Intensive Care Unit of the Guatemalan Institute of Social Security, between May and June 2021, and they were followed up to determine their discharge condition (deceased or recovered). ResultsTo determine the normality of the sample, the Kolmogorov-Smirnov statistic was used, followed by logistic regression to determine if there was an association between mortality and the following variables: dyslipidemia (p=0.224), total cholesterol (p=0.114), triglycerides (0.831) Conclusions: Although there are studies that prove an association between dyslipidemia and mortality due to COVID-19, in our study we did not find the same, therefore it is necessary to perform more studies to reach a consensus.