Abstract
to 157.7 10.6 nmol/l, p 0.014. In 8 of 12 experiments, the maximal 5HT level in coronary sinus blood was above 10 7 mol/l. 2) 5HT induced vasoconstriction in coronary artery segments after BD, whereas in controls, only a slight reaction was seen. In segments without endothelium, the vasoconstrictory effect of 5HT was more pronounced, but no significant difference between the BD and control group could be demonstrated, suggesting that endothelium is largely responsible for the differential reaction between BD and control dogs (figure).
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