Is DLKP a safe surgical method to treat corneal dystrophies?

Abstract

To compare the intraocular pressure (IOP)–lowering effect of combined viscocanalostomy and phacoemulsification and combined trabeculectomy and phacoemulsification with mitomycin C in eyes with primary open-angle glaucoma.Prospective randomized 1-year trial.Forty consecutive patients (40 eyes) with primary open-angle glaucoma and cataract.Eyes were assigned randomly either to trabeculectomy with mitomycin C or to viscocanalostomy in combination with phacoemulsification and intraocular lens implantation.Success rate based on IOP.Mean baseline IOP was 24.0±2.0 mmHg in the viscocanalostomy group and 23.7±2.6 mmHg in the trabeculectomy group (P = 0.7). Mean postoperative IOP was 13.7±2.2 mmHg at 3 months, 14.8±3.3 mmHg at 6 months, and 14.9±3.0 mmHg at 12 months in the viscocanalostomy group and 12.1±4.0 mmHg at 3 months, 13.8±4.7 mmHg at 6 months, and 14.1±4.4 mmHg at 12 months in the trabeculectomy group. There was no significant difference in the mean IOP between the groups at any time. At 12 months, 17 patients (85%) in the viscocanalostomy group and 16 patients (80%) in the trabeculectomy group achieved an IOP of 20 mmHg or less without medication (P = 0.7). Complications included 2 cases (10%) of flat/shallow anterior chamber and 4 cases (20%) of hypotony in the trabeculectomy group, whereas intraoperative microperforation of Descemet’s membrane occurred in 3 cases (15%) in the viscocanalostomy group.There was no significant difference in IOP reduction between viscocanalostomy and trabeculectomy with mitomycin C in combination with phacoemulsification and intraocular lens implantation in patients with primary open-angle glaucoma.