Abstract
<b>Introduction:</b> Access to in-clinic spirometry for patients with interstitial lung disease (ILD) has been restricted by the COVID19 pandemic. Remote monitoring of patient-recorded at-home spirometry & pulse oximetry offers an alternative approach to traditional hospital-based monitoring. <b>Objective:</b> To assess the feasibility of a remote monitoring programme (with spirometry & pulse oximetry) delivered within ILD clinical care settings for a 3-month period through assessment of adherence to study measurements. Methods: In this prospective, single-arm, observational study (NCT04850521), patients were asked to record 1 spirometry and pulse oximetry measurement per day for 91 days, using a digital health application (patientMpower™) & Bluetooth-linked devices. Patient-recorded data could be viewed in real time by their clinical teams via a secure, password-restricted web-based portal. Health-related quality of life and patient experience were also assessed. Results: 51 ILD patients enrolled and provided ≥1 spirometry reading. Baseline demographics: 35M/16F; 29 idiopathic pulmonary fibrosis (IPF)/22 non-IPF ILD; age: 67±12Y; in-clinic FVC: 84±20% predicted; TLCO 54±19% predicted (mean±SD); median modified ILD GAP score: 3. Patients recorded spirometry on median 92% of days & pulse oximetry on median 93% of days. To date, 30 patients have completed follow-up. 26/30 patients recorded spirometry and pulse oximetry ≥3 days/week & ≥70% of days. Conclusion: In this study, daily recording of home spirometry & pulse oximetry over 3 months appeared feasible. Further research is needed to understand how remote monitoring is best used within ILD clinical services. [Supported by Innovate UK (ref 66823)]
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