Abstract

The analysis provided of prospective studies of dynamics of the main cardiovascular risk factors (RF) from childhood until adulthood. The importance of such study is posed by insufficient effectiveness of prevention programs in adult population. Many issues not solved on the development of scientifically based approaches to early prevention in childhood and adolescence: what does facilitate RF formation, and what age is the most vulnerable? What determines resistibility of the RF and their transformation to adult life? What is the risk grade for CVD development in adult age, of children and adolescents? If in general it is clear, what population aim should be fulfilled for early CVD prevention: policy making, increase of a school importance, food industry reorganization, physical culture and sport programs realization, — it is still not known, what does determine RF stabilization or their spontaneous normalization. Solution of this issue could improve risk groups determination for preventive procedures.

Highlights

  • The analysis provided of prospective studies of dynamics of the main cardiovascular risk factors (RF) from childhood until adulthood

  • Many issues not solved on the development of scientifically based approaches to early prevention in childhood and adolescence: what does facilitate RF formation, and what age is the most vulnerable? What determines resistibility of the RF and their transformation to adult life? What is the risk grade for CVD development in adult age, of children and adolescents? If in general it is clear, what population aim should be fulfilled for early CVD prevention: policy making, increase of a school importance, food industry reorganization, physical culture and sport programs realization, — it is still not known, what does determine RF stabilization or their spontaneous normalization

  • В 60-е годы XX века была разработана теория о роли факторов риска (ФР) в развитии и течении сосудистые заболевания (ССЗ)

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Summary

Introduction

The analysis provided of prospective studies of dynamics of the main cardiovascular risk factors (RF) from childhood until adulthood. Корреляционный анализ связи АД в раннем подростковом возрасте и его уровнем в последующих периодах жизни показал, что все значения трекинг-коэффициентов (коэффициентов корреляции Пирсона) для САД у лиц обоего пола были статистически достоверными, но с устойчивой тенденцией к снижению их абсолютных значений от первого обследования к последнему: от 0,73 до 0,19 у мужчин и от 0,68 до 0,37 у женщин. Связь САД и толщины кожной складки над трицепсом (КСТ) у девушек отмечалась на всем протяжении 22-летнего проспективного наблюдения, а у юношей только в возрасте от 12-13 до 22-23 лет.

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