Abstract

“The clinical impact of aspirin resistance with cardiovascular events is now becoming evident, with aspirin nonresponders having nearly a threefold increased risk of cardiovascular death” Aspirin resistance is an increasingly recognized phenomenon denoting a diminished platelet inhibitory effect of aspirin. It has been reported in approximately 10–30% of patients taking aspirin. The clinical impact of aspirin resistance with cardiovascular events is now becoming evident, with aspirin nonresponders having nearly a threefold increased risk of cardiovascular death. The mechanisms for this phenomenon and methods to treat it are still unclear. More research is necessary before recommendations for clinical practice can be made. Aspirin was the first antiplatelet drug used in

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