Abstract
The medical management of ectopic pregnancy with methotrexate is geared towards resolution without the need for surgical intervention. Prior studies comparing single-dose and two-dose methotrexate (MTX) protocols found that a two-dose protocol is effective, particularly among patients with a high initial human chorionic gonadotropin (hCG) level [1-3]. However, there have been no studies comparing the outcome of single vs. two-dose MTX protocol for the treatment of an ectopic pregnancy in patients that conceive from IVF.
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