Is a R0 Resection Always the Aim in Resection of Colorectal Liver Metastasis?

Abstract

Introduction: Colorectal cancer is the 3rdmost common cancer in the UK, with up to 50% developing colorectal liver metastases (CRLM). When suitable, surgical resection of CRLM offers a five year survival of 35%-58%. Evidence remains equivocal regarding a superior surgical technique for resection or if synchronous colon and liver resections show more favourable results. Resection margin status is important, with recent evidence suggesting that an R1 resection often reflects more aggressive tumour biology.