Abstract
Objective: Recurrent cervical cancer (RCC) has a poor prognosis. Despite questionable benefit, treatment is often given at the expense of substantial toxicity. A panel of poor prognostic factors recently identified a high-risk group with an even worse prognosis. A prominent lung cancer study showed improved survival and quality of life (QOL) with treatment incorporation of home-based palliative care. We evaluated the comparative effectiveness of 4 management strategies for RCC: 1) standard combination chemotherapy for all (STD); 2) selective standard chemotherapy for low- to-intermediate risk patients, while high-risk patients receive home-based palliative care (SC); 3) single-agent chemotherapy plus home-based palliative care for all (C); and 4) home-based palliative care for all (H).
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