Abstract

Our antibiotic weaponry in the form of resistance inhibitors and combination therapies are proving a failure with the extensive drug resistance scenario leaving the multidrug resistance part far behind. Culture and sensitivity interpretation redefined. Scientific innovations get modified from time to time& so get interpretations. What is logic today may not be applicable tomorrow. We have to change as per the changing times & keep abreast with latest developments& incorporate need based surveillance and research tools in our systems otherwise wrongs would continue to happen.

Highlights

  • Global proliferation of antibiotic resistance to microbes is attributed to injudicious use of antibiotics at global, national & local levels

  • Consequent upon the four research studies done at SKIMS, Kashmir India on Esbl & Mbl assays showed an alarming increase in antibiotic resistance

  • Technologies to diagnose Esbl & Mbl must be incorporated in diagnostic systems routinely to avoid treatment failures & as such these antibiotics need to be prescribed with utmost caution & require strict physician & patient compliance

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Summary

Introduction

Global proliferation of antibiotic resistance to microbes is attributed to injudicious use of antibiotics at global, national & local levels. Consequent upon the four research studies done at SKIMS, Kashmir India on Esbl & Mbl assays showed an alarming increase in antibiotic resistance. Technologies to diagnose Esbl & Mbl must be incorporated in diagnostic systems routinely to avoid treatment failures & as such these antibiotics need to be prescribed with utmost caution & require strict physician & patient compliance.

Results
Conclusion

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