Abstract
L1 and L2 compression fractures. the γ-globulin region that was identified as an IgGλ protein by immunoelectrophoresis. Bone marrow examination showed a remarkable increase in the number of plasma cells (50%). Serum β-microglobulin level was increased to 4.68 mg/L. The patient was diagnosed with multiple myeloma stage IIIa. Two weeks after surgery the patient began chemotherapy with 2 cycles of vincristine, doxorubicin (Adriamycin; Pfizer, New York, NY, USA), and dexamethasone. This caused leucopenia and general weakness; it was replaced by a secondary therapy with bortezomib (Velcade; JanssenCilag, High Wycombe, UK), thalidomide, and dexamethasone. The patient responded well with no aggravating signs of multiple myeloma. The prognosis for women with multiple myeloma is poor, with a relative survival rate of 25% and 9% for 5 and 10 years, respectively [2]. The offspring of patients appear to be unaffected by the maternal disease [3].
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