Abstract
The sphenoid sinus was not recognized as a possible source of infection until 1905.<sup>1</sup>At that time and later (in 1908<sup>2</sup>), Onodi first described the anatomic connections between the posterior group of sinuses and the optic canal. As a result of his observations he felt that he had definitely established an etiologic relation between disturbances of vision and disease of the posterior ethmoid cells and the sphenoid sinuses. Loeb<sup>3</sup>in 1909 corroborated Onodi's work, and Schaeffer<sup>4</sup>in 1920 again emphasized this as a definite fact. They all showed that it is not uncommon for the posterior ethmoid cells and the sphenoid sinus to encroach on the optic canal, making it "abnormally small," a condition which may lead to serious pressure on the nerve, with ophthalmologic symptoms. In 1927, Crane<sup>5</sup>expressed the opinion that not only is there a likelihood of direct extension of infection from this relation but that simple
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