IRRADIATED BLOOD PRODUCTS-INSTITUTE PORTUGUESE OF ONCOLOGY – COIMBRA (IPOC) – EXPERIENCE OF BLOOD QUALITY ASSURANCE

Abstract

The risks and benefits in the transfusion medicine are a great challenges for blood quality assurance. They must be sufficient to support answers to the acute and late effects. The irradiation of blood components for avoid Graft Versus Host Disease (GVHD) isn't different. The Medicine Transfusional Service(MST) – IPOC have procedures considered of excellence in Portugal-Central that take a good prevention for DHEC. Goals: This work has with objectives introduce our procedures and results for irradiated blood components to Central Portugal region by 1 year. The MST-IPOC irradiated blood components (CE – erythrocyte concentrate, PP – platelets pool and CUP – platelet concentrate unit by apheresis) for internal and external hospitals use, principally to central region at Portugal and we work with Physical Medicine to maintain the quality of this service that is included in the European hemovigilance system. We has a IBL 437C irradiator since 1997 and use RAD-SURE type 25Gy hand tags and supporting labels of irradiation, separated records to internal and external irradiation, description step by step since activation doctor/technical staff and the pos tranfusional tracking of GVHD around all irradiated units in this service. Our results: 60 % CE, 70% PP and 100% CUP of all irradiated components are used in IPOC internally and 72% of those irradiated from external institutions were University Hospital of Coimbra. 94% and 6% CE, 93% and 7 % PP had irradiated for adults and children, respectively. In the evaluation of acute or late GVHD we hadnt been positive case notified in the last years. We considered that our answer are the result of our quality procedures and the good training in this process.