Abstract

Objectives To observe the iron overload and anemia in maintenance hemodialysis(MHD) patients, and investigate the relationship between them. Methods A retrospective single-center study of 120 MHD patients in the hospital from June 2014 to December 2014, who were divided into three groups: group A (SF≤500 mg/L, n=60), group B(500 mg/L 1000 mg/L, n=25)was performed.The dose of Erythropoietin(EPO) and intravenous iron, the change of hemoglobin(HB), urea nitrogen(BUN), creatinine(Cr), parathormone(PTH) and hipecidin were measured. Results The doses of intravenous iron and blood transfusion in group C were higher than the group A and B(P<0.05), the change of HB was higher in group A than in group B and C(P<0.05). Concentration of hepcidin was higher in group C than in group A and group B(P<0.05). Conclusions If SF≤500 mg/L, treatment of intravenous iron can effectively improve anemia in MHD patients, and if SF>1000 mg/L, it can not significantly improve patients’anemia and disorder of iron metabolism. Key words: Renal Dialysis; Iron; Anemia

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