Abstract
Background: Gestational diabetes mellitus (GDM) has been observed to be associated with increased perinatal morbidity and mortality. GDM affects approximately 7% of all pregnancies. The objective of the present study was to establish correlation of serum iron, phosphorous and hemoglobin levels in women with carbohydrate tolerance in gestational diabetes mellitus and to find out its association with gestational diabetes mellitus (GDM). Methods: The study involved screening of 100 pregnant women with gestational period of 24 – 28 weeks, for carbohydrate tolerance and prevalence of gestational diabetes mellitus. We estimated fasting glucose, post load glucose, serum iron, serum phosphorous, and hemoglobin in all 100 pregnant women selected for this study. The study was carried out in the department of OBG in collaboration with department of biochemistry. Results: In the present study, prevalence of Gestational Diabetes Mellitus is 8%. Both fasting and post serum glucose levels are significantly high in cases of Gestational Diabetes Mellitus. We observed increase in serum iron level for gestational diabetes mellitus mothers and is associated with carbohydrate tolerance. However, there was no correlation observed with phosphorous and hemoglobin levels in GDM mothers. Conclusion: Present study showed elevated serum iron levels correlates with the development of Gestational Diabetes Mellitus. Serum phosphorous and hemoglobin concentrations have not shown any significant variation.
Highlights
Gestational diabetes mellitus (GDM) is a disturbance in glucose metabolism, which is diagnosed during pregnancy and affects pregnant women [1]
The prevalence of gestational diabetes mellitus was 8%, which is comparable to the world wide prevalence
The prevalence of Gestational Diabetes Mellitus is 8% in cases attending the antenatal clinic in our teaching hospital
Summary
Gestational diabetes mellitus (GDM) is a disturbance in glucose metabolism, which is diagnosed during pregnancy and affects pregnant women [1]. Further maternal hyperglycemia has a direct effect on the fetal pancreas and is associated with the increased susceptibility to future diabetes in the infant. Women with a history of gestational diabetes mellitus as well as their children are at increased risk of future diabetes, predominantly type II diabetes [5]. Gestational diabetes mellitus (GDM) has been observed to be associated with increased perinatal morbidity and mortality. The objective of the present study was to establish correlation of serum iron, phosphorous and hemoglobin levels in women with carbohydrate tolerance in gestational diabetes mellitus and to find out its association with gestational diabetes mellitus (GDM)
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