Abstract
1. 1. Iron kinetics was studied on Siredon mexicanum originally from the valley of Mexico (7343 ft). 2. 2. Plasma iron clearance (T 1 2 59Fe) was estimated in 150 min. Circulating red-cells uptake was about 35 per cent. 3. 3. 59Fe bone marrow uptake had a peak after 2 hr of the radioisotope injection, with a later decrease. Spleen and liver increased their uptake up to a maximum between the first and the fifth day, with also a later decrease. 4. 4. It is concluded that mainly the spleen and in a lesser degree the liver and bone marrow are the most important organs of red-cell production in this animal. 5. 5. On the basis of the results obtained, we were able to compare axolotl erythropoiesis with that of the human foetus during the fourth to sixth lunar month of intra-uterine life.
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