Abstract

A simple, convenient and efficient three-component coupling (TCC) reaction toward a variety of (E)-2,3'-bi(3H-indol)-3-one oxime derivatives has been developed. This transformation proceeds via an iron (III)-catalyzed tandem coupling reaction between indoles and sodium nitrite. This methodology provides an alternative approach for easy access of (E)-2,3'-bi(3H-indol)-3-one oximes in good to excellent yields at room temperature.

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