Abstract
Introduction: Febrile seizures (FS) are a form of acute symptomatic seizures. Iron deficiency Anaemia (IDA) is one of the most common nutrition related problems in the world. Iron is important for neurological functions and development of brain. Methods: A case control study was done among 100 children at the Pediatric department, NRI Medical College & Hospital. Total of 100 children between age group of 6 months – 6 years with fever were included, out of which 50 children with first febrile seizure were enrolled as cases. 50 children with fever without seizure were enrolled as control group. A pre designed proforma was used to collect the relevant information. Blood samples collected from all cases and control groups and estimated for hematological parameters. Results: The mean age in months was 22.4 among cases and 26.7 months in controls. Nine cases had a positive family history of febrile seizures. Respiratory tract infections were most common underlying cause of illness. The mean and standard deviation values of all the hematological parameters (HB, PCV, MCV, MCH, MCHC & serum Ferritin) showed that measurements were lower among cases compared to control and it was statistically significant. Conclusions: IDA was more frequent among children with FS than those with febrile illness alone. The result suggests that IDA may be a risk factor for FS. Screening for IDA should be considered in children with First Febrile Seizures (FFS).
Highlights
Febrile seizures (FS) are a form of acute symptomatic seizures
A Febrile Seizure is defined by the International League Against Epilepsy (ILAE) as a “Seizure occurring in childhood after l month of age associated with a febrile illness not Manuscript received:15th March 2016 Reviewed: 25th March 2016 Author Corrected; 08th April 2016 Accepted for Publication: 17th April 2016 caused by an infection of central nervous system,without previous neonatal seizure or a previous unprovoked seizure and not meeting the criteria for other acute symptomatic seizure” [2]
All the parameters were lower among cases compared with controls which was found to be statistically significant (p
Summary
Febrile seizures (FS) are a form of acute symptomatic seizures. Iron deficiency Anaemia (IDA) is one of the most common nutrition related problems in the world. Over the past 25 years much more information on febrile seizures has accumulated and the prognosis for febrile seizures has been found to be excellent Such seizures are not associated with detectable brain damage and epilepsy will eventually develop in only a small minority of children who had FS. A Febrile Seizure is defined by the International League Against Epilepsy (ILAE) as a “Seizure occurring in childhood after l month of age associated with a febrile illness not Manuscript received:15th March 2016 Reviewed: 25th March 2016 Author Corrected; 08th April 2016 Accepted for Publication: 17th April 2016 caused by an infection of central nervous system ,without previous neonatal seizure or a previous unprovoked seizure and not meeting the criteria for other acute symptomatic seizure” [2]
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