Abstract
A series of complexes containing the iron-cyclopentadienone structure were prepared by cyclising bis-propargylic alcohols and their derivatives with iron pentacarbonyl. The resulting complexes were characterised and tested in the catalysis of ketone reduction and alcohol oxidation. The complexes are competent catalysts for ketone reduction and alcohol oxidations.
Highlights
There is a growing interest in the application of iron-based complexes for the catalysis of asymmetric transformations, primarily due to its relative low cost and toxicity relative to more commonly used catalysts based on precious metals
Iron cyclopentadienone complexes have recently emerged as promising reagents for hydrogenation reactions and for hydrogen transfer processes.2–13. Key to their application in this capacity is the formation of the derived hydrides of general structure 2, which can be achieved in situ using a number of activating agents, or through formation and isolation of the hydride prior to use
Gennari et al created a cleverly designed catalyst 8 derived from a binapthyl-scaffold, and this gave the highest asymmetric inductions so far recorded for ketone reduction with this class of complex; up to 77% in one case
Summary
C2-symmetric bis-propargylic alcohols; preparation and applications to catalysis†. A series of complexes containing the iron-cyclopentadienone structure were prepared by cyclising bis-. The complexes are competent catalysts for ketone reduction and alcohol oxidations. Www.rsc.org/dalton propargylic alcohols and their derivatives with iron pentacarbonyl.
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