Iron-catalyzed intermolecular C–C bond vinylation of cycloketoximes promoted by diboron

Abstract

An iron-catalyzed radical-mediated ring opening of cycloketoxime promoted by diboron compound is reported. This strategy provides alternative catalytic routes for the selective C–C bond vinylation, which provides effective approaches for the preparation of various distal-cyanoalkyl alkenes. The experimental explorations showed that the diboron reagent played important roles during the catalytic cycle. And a reasonable mechanism is proposed.