Abstract

BackgroundIris metastasis in patients with gastric cancer is extremely rare. Herein, it is aimed to report on a patient with gastric adenocarcinoma and iris metastasis.Case presentationA 65-year-old patient with the history of gastric cancer was admitted for eye pain and eye redness on his left eye. There was ciliary injection, severe +4 cells with hypopyon in the anterior chamber and a solitary, friable, yellow-white, fleshy-creamy vascularized 2 mm × 4 mm mass on the upper nasal part of the iris within the left eye. The presented patient’s mass lesion in the iris fulfilled the criteria of the metastatic iris lesion’s appearance. The ocular metastasis occurred during chemotherapy.ConclusionsIris metastasis can masquerade as iridocyclitis with pseudohypopyon or glaucoma. In patients with a history of gastric cancer that present with an iris mass, uveitis, and high intraocular pressure, ocular metastasis of gastric cancer should be a consideration.

Highlights

  • Iris metastasis in patients with gastric cancer is extremely rare

  • Iris metastasis can masquerade as iridocyclitis with pseudohypopyon or glaucoma

  • In patients with a history of gastric cancer that present with an iris mass, uveitis, and high intraocular pressure, ocular metastasis of gastric cancer should be a consideration

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Summary

Conclusions

Iris metastasis of a primary tumor originating from the gastric region is rare. The presented case shows that gastric adenocarcinoma can cause isolated metastasis in the iris. The presented case was diagnosed based on clinical history and ocular examination. In patients with a history of gastric cancer that presents with an iris mass, uveitis, and high IOP, ocular metastasis of gastric cancer should be considered. Consent Written informed consent was obtained from the parents of the deceased patient for publication of this case report and any accompanying images. AEK, UEA, and CBS carried out the literature review. ARC and AEK conceived of the study, participated in its design and coordination, and helped to draft the manuscript. CBS and AO have been involved in drafting the manuscript and revising it critically for important intellectual content. All authors read and approved the final manuscript

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