Abstract
Iridium-catalyzed azide-thioalkyne cycloaddition reaction (IrAAC) has proved to be a powerful tool for the synthesis of fully substituted 1,2,3-triazole compounds with exclusive regioselectivity. Here we report its successful use in the precise construction of stereocontrolled oligomers that have great potential in diverse applications. Starting with the azide derived from L-prolinol and different functionalized thioalkynes, chiral 1,2,3-triazole units were fabricated with high efficiency under the IrAAC condition, which were further assembled into stereocontrolled oligotriazoles through metal-free exponential growth strategies. The structure and uniformity of these oligomers were well identified by 1H NMR, size-exclusion chromatography, and mass spectrometry, the stereoregularity of which were studied through circular dichroism and circular polarized luminescence analysis.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
