Ipsilateral-mammogram computer-aided detection of breast cancer

Abstract

In this paper, an ipsilateral multi-view computer-aided detection (CAD) scheme is presented for mass detection in digital mammograms by exploiting correlative information of suspicious lesions between mammograms of the same breast. After nonlinear tree-structured filtering for image noise suppression, two wavelet-based methods, directional wavelet transform and tree-structured wavelet transform for image enhancement, and adaptive fuzzy C-means algorithm for segmentation are employed on each mammograms of the same breast, respectively, concurrent analysis is developed for iterative analysis of ipsilateral multi-view mammograms by inter-projective feature matching analysis. A supervised artificial neural network is developed as a classifier, in which the back-propagation algorithm combined with Kalman filtering is used as training algorithm, and free-response receiver operating characteristic analysis is used to test the performance of the developed unilateral CAD system. Performance comparison has been conducted between the final ipsilateral multi-view CAD system and our previously developed single-mammogram-based CAD system. The study results demonstrate the advantages of ipsilateral multi-view CAD method combined with concurrent analysis over current single-view CAD system on false positive reduction.