Abstract
Recent advances in Internet-of-Things technology have opened the doors to new scenarios for biosensor applications. Flexibility, portability, and remote control and access are of utmost importance to move these devices to people’s homes or in a Point-of-Care context and rapidly share the results with users and their physicians. In this paper, an innovative portable device for both quantitative and semi-quantitative electrochemical analysis is presented. This device can operate autonomously without the need of relying on other devices (e.g., PC, tablets, or smartphones) thanks to built-in Wi-Fi connectivity. The developed hardware is integrated into a cloud-based platform, exploiting the cloud computational power to perform innovative algorithms for calibration (e.g., Machine Learning tools). Results and configurations can be accessed through a web page without the installation of dedicated APPs or software. The electrical input/output characteristic was measured with a dummy cell as a load, achieving excellent linearity. Furthermore, the device response to five different concentrations of potassium ferri/ferrocyanide redox probe was compared with a bench-top laboratory instrument. No difference in analytical sensitivity was found. Also, some examples of application-specific tests were set up to demonstrate the use in real-case scenarios. In addition, Support Vector Machine algorithm was applied to semi-quantitative analyses to classify the input samples into four classes, achieving an average accuracy of 98.23%. Finally, COVID-19 related tests are presented and discussed.
Highlights
The recent development of Information and Communications Technologies (ICT), designed for the Internet of Things (IoT) framework, has led to an increased interest in the study of new smart, portable, and interconnected devices in different application fields [1], [2]
This paper presents a smart, portable, and cloud-based reconfigurable potentiostat for both semi-quantitative and quantitative analyses
From the implementations reported in the literature, the device architecture includes cloud services, with a web service acting as the interface between the cloud and the user devices (e.g. PC, tablet, smartphone)
Summary
The recent development of Information and Communications Technologies (ICT), designed for the Internet of Things (IoT) framework, has led to an increased interest in the study of new smart, portable, and interconnected devices in different application fields [1], [2]. Electrochemical analyses and, in particular, biosensing applications are not an exception [3]–[5]. With the advent of IoT technologies, it is possible to design new portable potentiostats that open the doors to innovative features. The possibility of moving these devices to different locations will bring the laboratory closer to people's homes, according to a Point-ofCare (PoC) context, allowing periodic analyses more (e.g. follow-up of a particular pathology) or the immediate sharing of the results with the physicians [8].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
